Zurro et al. Synthesis 2023: Visible-Light-Mediated Regioselective Chlorosulfonylation of Acrylamides.

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Publicaciones > Zurro et al

Visible-Light-Mediated Regioselective Chlorosulfonylation of Acrylamides.

Resumen

A one-step chlorosulfonylation of acrylamides via a photocatalytic redox process is described. This reaction provides α-chlorosulfonylamides with a quaternary center with high regioselectivity via radical process. It is amenable to a broad range of substrates and the products are obtained in moderate to good yields.

graphical abstract