Publicaciones

Publicaciones

2022
Synthesis of Phenanthrene-Based Polycycles by Gold(I)-Catalyzed Cyclization of Biphenyl-Embedded Trienynes.
Adv. Synth. Catal. 2022; 364, 3960-3966, doi:10.1002/adsc.202200887.
Gold(I) Catalysis Applied to the Stereoselective Synthesis of Indeno%@5B2,1-b%@5Dthiochromene Derivatives and Seleno Analogues /
Org. Lett. 2022, doi: 10.1021/acs.orglett.2c03411.
Highly efficient unbridged D-A%@2B(D) chromophores based on the quinolizinium cation for nonlinear optical (NLO) applications /
Dyes and Pigments 2022, 205, 110323. doi: 10.1016/j.dyepig.2022.110323.
Synthesis of BN-Polyarenes by a Mild Borylative Cyclization Cascade.
Org Lett. 2022;24(31):5860-5865. doi: 10.1021/acs.orglett.2c02477.
Steviol glycosides as an alternative osmotic agent for peritoneal dialysis fluid.
Front Pharmacol. 2022 Aug 16;13:868374. doi: 10.3389/fphar.2022.868374. eCollection 2022.
Synthesis of Tri- and Tetrasubstituted Alkenyl Boronates from Alkynes /
Eur. J. Org. Chem. 2022; e202200521. doi:10.1002/ejoc.202200521
Metal-Free Temperature-Controlled Regiodivergent Borylative Cyclizations of Enynes: BCl(3) -Promoted Skeletal Rearrangement.
Angew Chem Int Ed Engl. 2022 May 5:e202205651. doi: 10.1002/anie.202205651.
Electrochemically driven one-pot oxidative conversion of arylhydrazines into aromatic iodides /
J. Environ. Chem. Eng. 2022; 10(3):107486.
RICORS2040: the need for collaborative research in chronic kidney disease.
Clin Kidney J. 2022 Sep 23;15(3):372-387. doi: 10.1093/ckj/sfab170.
CKD: The burden of disease invisible to research funders.
Nefrologia. 2022 Jan-Feb;42(1):65-84. doi: 10.1016/j.nefro.2021.09.004.
Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase.
Eur J Med Chem. 2022 Jan 5;227:113915. doi: 10.1016/j.ejmech.2021.113915.

2021
1,10a-Dihydro-1-aza-10a-boraphenanthrene and 6a,7-Dihydro-7-aza-6a-boratetraphene: Two New Fluorescent BN-PAHs.
J Org Chem. 2021 Nov 22. doi: 10.1021/acs.joc.1c01095.
Two-photon activated precision molecular photosensitizer targeting mitochondria.
Commun. Chem. 2021; 4(1):142. doi: 10.1038/s42004-021-00581-4
A Computer-Driven Scaffold-Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo%1,2-a%quinoxaline Core.
ChemMedChem. 2021 Sep 16;16(18):2895-2906. doi: 10.1002/cmdc.202100338. Epub 2021 Jul 19.
Chemical recovery of waste electrical and electronic equipment by microwave-assisted pyrolysis: A review.
J Anal Appl Pyrolysis 2021; 159:105323. doi: 10.1016/j.jaap.2021.105323
Enantioselective Copper-Catalyzed Synthesis of Trifluoromethyl-Cyclopropylboronates.
Org Lett. 2021 Aug 6;23(15):6174-6178. doi: 10.1021/acs.orglett.1c02420.
Pyrrolo%1,2-a%quinoxal-5-inium salts and 4,5-dihydropyrrolo%1,2-a%quinoxalines: Synthesis, activity and computational docking for protein tyrosine phosphatase 1B.
Bioorg Med Chem. 2021 Jul 3; 44:116295.
Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein-Protein Interaction with α-Parvin.
ACS Med Chem Lett. 2021 Jul 15;12(11):1656-1662. doi: 10.1021/acsmedchemlett.1c00183.
Recent developments in the chemistry of BN-aromatic hydrocarbons.
Adv. Heterocycl. Chem. 2021 Mar 28; :197-259.
A new family of fluorescent pyridazinobenzimidazolium cations with DNA binding properties.
Dyes and Pigments. 2021 Aug 1; :109443. doi: 10.1016/j.dyepig.2021.109443
Asymmetric, visible light-mediated radical sulfinyl-Smiles rearrangement to access all-carbon quaternary stereocentres.
Nat Chem. 2021 Apr;13(4):327-334. doi: 10.1038/s41557-021-00668-4.

2020
Selective Synthesis of Phenanthrenes and Dihydrophenanthrenes via Gold-Catalyzed Cycloisomerization of Biphenyl Embedded Trienynes.
Org Lett. 2020 Nov 6;22(21):8464-8469. doi: 10.1021/acs.orglett.0c03067.
Gold-Catalyzed Synthetic Strategies towards Four-Carbon Ring Systems.
Catalysts. 2020 Oct 8; 22(21):1178.
Pyrrolo%1,2-a%quinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B.
ChemMedChem. 2020 Sep 10. doi: 10.1002/cmdc.202000446.
The pHLIP system as a vehicle for microRNAs in the kidney.
Nefrologia. 2020 Jul 18:S0211-6995(20)30084-9. doi: 10.1016/j.nefro.2020.05.007.
Practical Solvent-Free Microwave-Assisted Hydroboration of Alkynes.
Eur. J. Org. Chem. 2020 May 26:3024-3029. doi: 10.1002/ejoc.202000110.
Expanding the BN-embedded PAH family: 4a-aza-12a-borachrysene.
Chem Commun (Camb). 2020 Mar 28;56(25):3669-3672. doi: 10.1039/c9cc09998k.
Synthesis and Photophysical Behavior of a Highly Fluorescent Family of Unsymmetrical Organoboron Complexes Containing 5-(Pyridin-2-ylmethylene)imidazolidine-2,4-dione Moieties.
J Org Chem. 2020 Jan 17;85(2):441-448. doi: 10.1021/acs.joc.9b02451.

2019
A New Member of the BN-Phenanthrene Family: Understanding the Role of the B-N Bond Position.
J Org Chem. 2019 Jun 7;84(11):7113-7122. doi: 10.1021/acs.joc.9b00800. Epub 2019 May 23.
Remarkable effect of alkynyl substituents on the fluorescence properties of a BN-phenanthrene.
Beilstein J Org Chem. 2019 Jun 6;15:1257-1261. doi: 10.3762/bjoc.15.122. eCollection 2019.
NIK as a Druggable Mediator of Tissue Injury.
Trends Mol Med. 2019 Apr;25(4):341-360. doi: 10.1016/j.molmed.2019.02.005. Epub 2019 Mar 26.
Synthesis, Functionalization, and Optical Properties of 1,2-Dihydro-1-aza-2-boraphenanthrene and Several Highly Fluorescent Derivatives.
Org Lett. 2019 Apr 19;21(8):2550-2554. doi: 10.1021/acs.orglett.9b00448. Epub 2019 Apr 5.
Regiodivergent Electrophilic Cyclizations of Alkynylcyclobutanes for the Synthesis of Cyclobutane-Fused O-Heterocycles.
J Org Chem. 2019 Apr 18. doi: 10.1021/acs.joc.9b00618.
MAP3K kinases and kidney injury.
Nefrologia. 2019 Nov - Dec;39(6):568-580. doi: 10.1016/j.nefro.2019.03.004.

2018
Discovery of potent calpain inhibitors based on the azolo-imidazolidenone.
Eur J Med Chem. 2018 Sep 5;157:946-959. doi: 10.1016/j.ejmech.2018.08.045.
C-H Functionalization of BN-Aromatics Promoted by Addition of Organolithium Compounds to the Boron Atom.
Org Lett. 2018 Aug 17;20(16):4902-4906. doi: 10.1021/acs.orglett.8b02040.
gamma-Carboline Synthesis by Heterocyclization of TosMIC Derivatives.
J Org Chem. 2018 Jun 15;83(12):6623-6632. doi: 10.1021/acs.joc.8b00906. Epub 2018 May 24.
A Tricin Derivative from Deschampsia antarctica Desv. Inhibits Colorectal Carcinoma Growth and Liver Metastasis through the Induction of a Specific Immune Response.
Mol Cancer Ther. 2018 May;17(5):966-976. doi: 10.1158/1535-7163.MCT-17-0193.
Dibenzopyridoimidazocinnolinium cations: a new family of light-up fluorescent DNA probes.
Org. Chem. Front. 2018 May 2; 5(12):1916-1927. doi: 10.1039/C8QO00236C
Synthesis of functionalized helical BN-benzo%c%phenanthrenes.
Chem Commun (Camb). 2018 Mar 6;54(20):2467-2470. doi: 10.1039/c7cc09264d.

2017
Azonia aromatic heterocycles as a new acceptor unit in D-π-A+ vs D-A+ nonlinear optical chromophores.
Dyes & Pigments, 2017 Sep 1;144:17-31. doi: 10.1016/10.1016/j.dyepig.2017.05.005.
Microwave-assisted pyrolysis of Mediterranean forest biomass waste: Bioproduct characterization.
J. Anal. Appl. Pyrolysis, 2017 Sep 1;127:278-285. doi: j.jaap.2017.07.024.
Synthesis, Optical Properties, and Regioselective Functionalization of 4a-Aza-10a-boraphenanthrene.
Org Lett. 2017 Jul 7;19(13):3458-3461. doi: 10.1021/acs.orglett.7b01435.
Imidazopyridinium cations: A new family of azonia aromatic heterocycles with applications as DNA intercalators.
Dyes & Pigments, 2017 Mar 1;138:135-146. doi: 10.1016/j.dyepig.2016.11.041.
Quinolizinium as a new fluorescent lysosomotropic probe.
Biorg. Med. Chem. Lett., 2017 Jan 15;27(2):203-207. doi: 10.1016/j.bmcl.2016.11.074.
Halogen-containing thiazole orange analogues - new fluorogenic DNA stains.
Beilstein J Org Chem. 2017 Dec 28;13:2902-2914. doi: 10.3762/bjoc.13.283.

2016
Recent Advances in the Synthesis of Azonia Aromatic Heterocycles.
J Org Chem. 2016 Nov 4;81(21):10126-10135. doi: 10.1021/acs.joc.6b01092. Epub 2016 Jul 18.
Synthesis of 1-Substituted Isoquinolines by Heterocyclization of TosMIC Derivatives: Total Synthesis of Cassiarin A.
Org Lett. 2016 Jul 15;18(14):3378-81. doi: 10.1021/acs.orglett.6b01521. Epub 2016 Jun 28.

2015
Highly Fluorescent Green Fluorescent Protein Chromophore Analogues Made by Decorating the Imidazolone Ring.
Chemistry. 2015 Dec 14;21(51):18758-63. doi: 10.1002/chem.201502929. Epub 2015 Nov 3.
Assembly of New Merocyanine Chromophores with a 1,8-Naphthalimide Core by a New Method for the Synthesis of the Methine Function.
Australian Journal of Chemistry. 2015 Aug 25; :1399-1408.
Nonlinear Emission of Quinolizinium Based Dyes With Application in Fluorescence Lifetime Imaging.
The Journal of Physical Chemistry A. 2015 Aug 18; :2351-2362.
Azonia Aromatic Cations by Ring-Closing Metathesis: Synthesis ofAzaquinolizinium Cations.
Eur J Org Chem. 2015 Jun 24; 6(24):4214-4223.
Synthesis and biological evaluation of pyridazino%1′,6′:1,2%pyrido%3,4-b%indolinium and pyridazino%1,6-a%benzimidazolium salts as anti-inflammatory agents.
Eur. J. Med. Chem. 2015 Mar; :83-92.
Isoquinoline synthesis by heterocyclization of tosylmethyl isocyanide derivatives: total synthesis of mansouramycin B.
Org Lett. 2015 Jan 2;17(1):78-81. doi: 10.1021/ol5032624. Epub 2014 Dec 18.
Targeting DNA with small molecules: a comparative study of a library of azonia aromatic chromophores.
Org Biomol Chem. 2015 Jan 14;13(2):527-38. doi: 10.1039/c4ob01465k. Epub 2014 Nov 7.

2014
Efficient synthesis of an indoloquinolizinium alkaloid selective DNA-binder by ring-closing metathesis.
Org Lett. 2014 Jul 3;16(13):3464-7. doi: 10.1021/ol5013668.
Microwave-assisted synthesis of potent PDE7 inhibitors containing a thienopyrimidin-4-amine scaffold.
Org Biomol Chem. 2014 Jun 28;12(24):4233-42. doi: 10.1039/c4ob00175c.
Cucurbit%n%urils as a potential fine-tuned instrument for modifying photophysical properties of D–π–A+–π–D “push–pull” chromophores.
Dyes and Pigments. 2014 Apr 1; :106-117. doi: 10.1016/j.dyepig.2013.12.003
Novel charged NLO chromophores based on quinolizinium acceptor units.
Dyes and Pigments. 2014 Feb 1; :116-121. doi: 10.1016/j.dyepig.2013.09.031

2013
Remote aryl cyanation via isocyanide-cyanide rearrangement on tosylmethyl isocyanide derivatives.
Org Lett. 2013 Jul 5;15(13):3388-91. doi: 10.1021/ol401433x.
Synthesis of charged bis-heteroaryl donor-acceptor (D-A+) NLO-phores coupling (π-deficient-π-excessive) heteroaromatic rings.
Org. Biomol. Chem. 2013; 11(41):7145 -7154. doi: 10.1039/c3ob41159a
Fluorescent Dyes for Bio-Applications in the Patent Literature / Fluorescent Dyes for Bio-Applications in the Patent Literature
Current Materials Science. 2013; 6(2):81 -119. doi: 10.2174/1874464811306020001
Synthesis and evaluation of quinazoline derivatives as phosphodiesterase 7 inhibitors.
Bioorg. Med. Chem. 2013; 21(8):2370 -2378. doi: 10.1016/j.bmc.2013.01.067

2012
A cascade reaction of azolopyrimidines. Synthesis of unusual indole and azaindole derivatives.
Chem. Commun. 2012 Jul 23;48:9171–9173. doi: 10.1039/c2cc34539k.
Donor-(π-bridge)-azinium as D-π-A + one-dimensional and D-π-A +-π-D multidimensional V-shaped chromophores.
Org. Biomol. Chem. 2012; 10(8):1659 -1669. doi: 10.1039/c2ob06427h
Superior Neuroprotective Efficacy of LAU-0901, a Novel Platelet-Activating Factor Antagonist, in Experimental Stroke.
Translational Stroke Research 2012; 3(1):154 -163. doi: 10.1007/s12975-011-0116-y
Synthesis of 9,9′-%1,2-Ethanediylbis(oxymethylene)%bis-2-amino-1,9-dihydro-6H-purin-6-one, an Impurity of Acyclovir.
Molecules. 2012; 17(8). doi: 10.3390/molecules17088735
New losartan-hydrocaffeic acid hybrids as antihypertensive-antioxidant dual drugs: Ester, amide and amine linkers
Eur. J. Med. Chem 2012; 50:90 -101. doi: 10.1016/j.ejmech.2012.01.043.

2011
A V-shaped cationic dye for nonlinear optical bioimaging.
Chemical Communications. 2011; 47(26):7374 -7376.
Radical Intramolecular Arylation of Pyridinium Salts: A Straightforward Entry to 7-Hydroxypyrido%2,1‐a%isoquinolinylium Salts /
European Journal of Organic Chemistry. 2011; 2011(3):619-628. doi: 10.1002/ejoc.201001071
Ethyl 4,4-dimethyl pyroglutamate (DMPG): A chiral auxiliary in cyclopropanation and carbonyl group activator.
Arkivoc. 2011;(3), 42-53. doi: 10.3998/ark.5550190.0012.305
Novel linear and V-shaped D-π-A+-π-D chromophores by Sonogashira reaction.
Arkivoc. 2011;(3):140-155. doi: 10.3998/ark.5550190.0012.311
An environmentally benign procedure for the synthesis of substituted 2-thiobenzothiazoles, 2-thiobenzoxazoles, 2-thiobenzimidazoles, and 1,3-oxazolopyridine-2-thiols.
Monatsh. Chem. 2011; 142(9):895. doi: 10.1007/s00706-011-0551-1
Synthesis of novel tetracationic asymmetric monomeric monomethine cyanine dyes – highly fluorescent dsDNA probes /
Coloration Technology. 2011; 127(1):69-74. doi: 10.1111/j.1478-4408.2010.00280.x
Environmental Risk Assessment of Emerging Pollutants in Water: Approaches Under Horizontal and Vertical EU Legislation /
Critical Reviews in Environmental Science and Technology. 2011; 41(7):699-731. doi: 10.1080/10643380903140224
Ring-Closing Metathesis Approach to Heteroaromatic Cations: Synthesis of Benzo%a%Dquinolizinium Salts /
European Journal of Organic Chemistry. 2011; 2011(7):1280 -1290. doi: 10.1002/ejoc.201001373

2010
Heteroaromatic Cation-Based Chromophores: Synthesis and Nonlinear Optical Properties of Alkynylazinium Salts /
European Journal of Organic Chemistry. 2010; 2010(33):6323-6330. doi: 10.1002/ejoc.201000816
Application of Selective Palladium-Mediated Functionalization of the Pyrido%@5B3′,2′:4,5%@5Dpyrrolo%@5B1,2-c%@5Dpyrimidine Heterocyclic System for the Total Synthesis of Variolin B and Deoxyvariolin B /
European Journal of Organic Chemistry. 2010; 2010(29):5607-5618. doi: 10.1002/ejoc.201000599
Novel Green Procedure for the Synthesis of 2-Arylbenzothiazoles Under Microwave Irradiation in Peg 200 Or Peg 400 /
Phosphorus, Sulfur, and Silicon and the Related Elements. 2010; 185(11):2292-2302. doi: 10.1080/10426501003598648
Styryl dyes – synthesis and applications during the last 15 years /
Coloration Technology. 2010; 126(2):55-80. doi: 10.1111/j.1478-4408.2010.00235.x
Green chemistry in organic synthesis.
Mini-Reviews in Organic Chemistry. 2010; 7(1):44 -53.
Novel environmentally benign procedure for the synthesis of 2-aryl- and 2-hetaryl-4(3H)-quinazolinones /
Coloration Technology. 2010; 126(1):24-30. doi: 10.1111/j.1478-4408.2010.00223.x
An easy and fast ultrasonic selective S-alkylation of hetaryl thiols at room temperature /
Ultrasonics Sonochemistry 2010; 17(5):783-788. doi: 10.1016/j.ultsonch.2010.03.002

Publicaciones