Synthesis of BN-Polyarenes by a Mild Borylative Cyclization Cascade
Ester Sans-Panadés, Juan J. Vaquero, Manuel A. Fernández-Rodríguez*, Patricia García-García*
Org. Lett. 2022, ASAP
DOI: 10.1021/acs.orglett.2c02477
| Reaction of BCl3 with suitably substituted o-alkynylanilines promotes a cascade reaction in which BN-polycyclic compounds are obtained via the formation of two new cycles and three new bonds in a single operational step. The reaction is highly efficient and takes place at room temperature, providing a very mild and straightforward strategy for the preparation of BN-aromatic compounds, which can be further transformed into a variety of BN-PAHs with different polycyclic cores and substituents. |