Castillo et al. European Journal of Organic Chemistry. 2011;2011(3):619 -628. Radical Intramolecular Arylation of Pyridinium Salts: A Straightforward Entry to 7-Hydroxypyrido[2,1‐a]isoquinolinylium Salts

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Radical Intramolecular Arylation of Pyridinium Salts: A Straightforward Entry to 7-Hydroxypyrido[2,1‐a]isoquinolinylium Salts

Resumen

The synthesis of 7-hydroxypyrido[2,1‐a]isoquinolinylium salts can be achieved in moderate yields by intramolecular radical arylation of pyridinium salts obtained from substituted pyridines and o-bromophenacyl bromides.

graphical abstract