Thesis defense, 22.09.2023 (“Estudio de la reactividad del 2,2,2-trifluorodiazoetano en la síntesis de ciclopropanos y pirazoles y en la funcionalización de alcanos”)
Predoctoral stay, Prof. John F. Hartwig (University of California, Berkeley)
FPU grant Ministerio de Educación y Formación Profesional 2019-2023
Master Drug Discovery Universidad de Alcalá (2018/2019)
Graduated at the Universidad de Jaén (2014-2018)
Publications in the group
One-Pot (3 + 2) Cycloaddition-Isomerization-Oxidation of 2,2,2-Trifluorodiazoethane and Styryl Derivatives.
Julia Altarejos, Estíbaliz Merino, David Sucunza, Juan J Vaquero, Javier Carreras
2019-present: Senior Research Fellow , Talent Attraction Program of Community of Madrid-Type 1, Universidad de Alcalá (Madrid)
2013-2019: Associated Researcher, University of Zurich (Switzerland) (Prof. Cristina Nevado). Development of new methodologies in organic synthesis and study of reaction mechanisms through computational calculations.
2011-2013: «JAE-Doc» Researcher, Instituto de Química Orgánica General (IQOG-CSIC) (Madrid) (Prof. Félix Sánchez). Design and synthesis of new functionalized micro and mesoporous organic materials.
2010-2011: «Juan de la Cierva» Researcher, Instituto de Tecnología Química (ITQ, CSIC-UPV) (Prof. Avelino Corma). Development and study of the properties of new multifunctional hybrid materials.
2007-2009: Postdoctoral Researcher, RWTH Aachen University (Germany) (Prof. Magnus Rueping).
2007: Ph.D. Universidad Autónoma de Madrid (Prof. Mª Carmen Carreño) Nuevas Aplicaciones de los Sulfóxidos: Síntesis de Moléculas Naturales a partir de p-(tolilsulfinilmetil)-p-Quinoles. Síntesis y Propiedades Fotocrómicas de Sulfinil Azocompuestos Enantiopuros.
2000: Graduated at the Universidad Autónoma de Madrid.
Thesis defense, 12.04.24. “Síntesis de aminoácidos bicíclicos y peptidomiméticos conformacionalmente restringidos derivados de prolina y ácido pipecólico”
Predoctoral stay, Prof. Maria Laura Bolognesi (BoMedChem Lab, Alma Mater Studiorum – Università di Bologna)
Expanding the BN-embedded PAH family: 4a-aza-12a-borachrysene.
Alberto Abengozar, Isabel Valencia, Guillermo G Otarola, David Sucunza, Patricia Garcia-Garcia, Adrian Perez-Redondo, Francisco Mendicuti, Juan J Vaquero
2023-Present: Assistant Professor, Universidad de Alcalá.
2022-2023:’Margarita Salas’ Postdoctoral Research Fellow, University of Bath (United Kingdom) (Prof. Carmen Domene).
2020-2022: Postdoc Sonsoles Martín Santamaría group, Centro de Investigaciones Biológicas Margarita Salas (CIB-CSIC). Thesis defense, 23.09.2020.
2018: Predoctoral stay at University of Bristol, Center for Computational Chemistry, (United Kingdom) (Prof. Adrian. J. Mulholland).
2017-2020 FPU grant MINECO.
2016-2017: FPI grant Universidad de Alcalá.
2015: Master Drug Discovery, Universidad Complutense de Madrid.
2014: Graduated (Pharmacy) at the Universidad Complutense de Madrid.
2013: CNIO Summer Training Program Fellow at Spanish National Cancer Research Center (CNIO) / Experimental Therapeutics Programme, Medicinal Chemistry Section (Dr. Joaquín Pastor / Sonia Martínez).
Publications in the group
Insight into the mechanism of molecular recognition between human Integrin-Linked Kinase and Cpd22 and its implication at atomic level.
Javier García-Marín, Diego Rodríguez-Puyol, Juan J Vaquero
Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase.
Héctor de Lucio, Javier García-Marín, Patricia Sánchez-Alonso, Juan Carlos García-Soriano, Miguel Ángel Toro, Juan J Vaquero, Federico Gago, Ramón Alajarín, Antonio Jiménez-Ruiz
Pyrrolo%1,2-a%quinoxal-5-inium salts and 4,5-dihydropyrrolo%1,2-a%quinoxalines: Synthesis, activity and computational docking for protein tyrosine phosphatase 1B.
Patricia Sánchez-Alonso, Mercedes Griera, Javier García-Marín, Manuel Rodríguez-Puyol, Ramón Alajarín, Juan J Vaquero, Diego Rodríguez-Puyol
Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein-Protein Interaction with α-Parvin.
Javier Garcia-Marin, Mercedes Griera-Merino, Alejandra Matamoros-Recio, Sergio de Frutos, Manuel Rodríguez-Puyol, Ramón Alajarín, Juan J Vaquero, Diego Rodríguez-Puyol
Pyrrolo%@5B1,2-a%@5Dquinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B.
Javier García-Marín, Mercedes Griera, Patricia Sánchez-Alonso, Bruno Di Geronimo, Francisco Mendicuti, Manuel Rodríguez-Puyol, Ramón Alajarín, Beatriz de Pascual-Teresa, Juan J Vaquero, Diego Rodríguez-Puyol
orcid.org/0000-0002-7265-4113
