Category Archives: Miembros

Rubén Manzano

Rubén Manzano San José

Assistant Professor

    • Associated Professor, Universidad de Valladolid (2022)
    • Assistant Professor, Universidad de Alcalá (2019-2022)
    • Postdoctoral researcher, Prof. J. L. Vicario group, Universidad del País Vasco (2017-2019)
    • Marie-Curie Fellowship, Prof. D. J. Dixon group, Universidad de Oxford (2015-2017)
    • Postdoctoral researcher ICIQ-IPMP, Prof. R. Martín group, ICIQ (2013-2015)
    • Postdoctoral researcher, Prof. A. S. K. Hashmi group, CaRLa-Universidad de Heidelberg (2011-2013)
    • Ph.D. Universidad de Valladolid (2010), supervisors Prof. R. Pedrosa and Prof. J. M. Andrés
    • Graduated at the Universidad de Valladolid (2005)

    I developed my PhD Thesis at the Universidad de Valladolid on the synthesis of chiral thioureas derived from amino acids and their applications as organocatalysts in enantioselective reactions of interest. Later, as postdoctoral researcher in the groups of Prof. A. S. K. Hashmi and Prof. R. Martín, I developed synthetic methodologies with gold, ruthenium, nickel and palladium catalysis. I then obtained a prestigious Marie-Curie Fellowship to carry out a project of dual enantioselective catalysis (aminocatalysis and metal catalysis with silver and copper) in the laboratories of Prof. D. J. Dixon at Oxford University. After this stage, I joined Prof. J. L. Vicario’s group at the Universidad del País Vasco as a contracted researcher, where I worked on the discovery of new reactivity patterns by enantioselective catalysis by phosphoric acids and by chiral phosphines, as well as on the synthesis of natural products. In October 2019 I joined the Universidad de Alcalá as Assistant Professor. The results of my research are collected in twenty publications, most of them with a high impact rate (ACIE (3), JACS (2), CEJ (3)…). During my research career I have supervised many students during the completion of their Master thesis and Bachelor thesis, as well as during external internships.

  • Clara Mañas

    Clara Mañas

    • Project associate researcher (2024)
    • Thesis defense, 04.03.2024 (“Design and study of novel reactivities of alkynylazobenzenes”)
    • Project associate researcher. Department of Organic and Inorganic Chemistry
    • Master Organic Synthesis Universidad Autónoma de Madrid (2018/2019)
    • Graduated at the Universidad Complutense de Madrid (2014-2018)

    Publicaciones en el grupo

    Visible Light-Mediated Heterodifunctionalization of Alkynylazobenzenes for 2H-Indazole Synthesis.
    Org Lett. 2024, 26, 1868
    Electrochemically driven one-pot oxidative conversion of arylhydrazines into aromatic iodides.
    J. Environ. Chem. Eng. 2022, 10, 107486

    Julia Altarejos

    Julia Altarejos

    • Thermo Fisher Scientific 04.2024
    • Postdoctoral Researcher (2023-2024)
    • Thesis defense, 22.09.2023 (“Estudio de la reactividad del 2,2,2-trifluorodiazoetano en la síntesis de ciclopropanos y pirazoles y en la funcionalización de alcanos”)
    • Predoctoral stay, Prof. John F. Hartwig (University of California, Berkeley)
    • FPU grant Ministerio de Educación y Formación Profesional 2019-2023
    • Master Drug Discovery Universidad de Alcalá (2018/2019)
    • Graduated at the Universidad de Jaén (2014-2018)

    Publications in the group

    One-Pot (3 + 2) Cycloaddition-Isomerization-Oxidation of 2,2,2-Trifluorodiazoethane and Styryl Derivatives.
    J Org Chem. 2023, 88, 11258
    Synthesis of Tri- and Tetrasubstituted Alkenyl Boronates from Alkynes.
    Eur. J. Chem. 2022, e202200521.
    Enantioselective Copper-Catalyzed Synthesis of Trifluoromethyl-Cyclopropylboronates.
    Org Lett. 2021 Aug 6;23(15):6174-6178. doi: 10.1021/acs.orglett.1c02420.
    Practical Solvent-Free Microwave-Assisted Hydroboration of Alkynes.
    Eur. J. Org. Chem. 2020, 3024

    Estibaliz Merino

    Estibaliz Merino Marcos

    Associate Professor

      • 2019-present: Senior Research Fellow , Talent Attraction Program of Community of Madrid-Type 1, Universidad de Alcalá (Madrid)
      • 2013-2019: Associated Researcher, University of Zurich (Switzerland) (Prof. Cristina Nevado). Development of new methodologies in organic synthesis and study of reaction mechanisms through computational calculations.
      • 2011-2013: «JAE-Doc» Researcher, Instituto de Química Orgánica General (IQOG-CSIC) (Madrid) (Prof. Félix Sánchez). Design and synthesis of new functionalized micro and mesoporous organic materials.
      • 2010-2011: «Juan de la Cierva» Researcher, Instituto de Tecnología Química (ITQ, CSIC-UPV) (Prof. Avelino Corma). Development and study of the properties of new multifunctional hybrid materials.
      • 2007-2009: Postdoctoral Researcher, RWTH Aachen University (Germany) (Prof. Magnus Rueping).
      • 2007: Ph.D. Universidad Autónoma de Madrid (Prof. Mª Carmen Carreño) Nuevas Aplicaciones de los Sulfóxidos: Síntesis de Moléculas Naturales a partir de p-(tolilsulfinilmetil)-p-Quinoles. Síntesis y Propiedades Fotocrómicas de Sulfinil Azocompuestos Enantiopuros.
      • 2000: Graduated at the Universidad Autónoma de Madrid.

    Francisco Maqueda

    Francisco Maqueda

    • Center for Applied Chemistry and Biotechnology – UAH (2024-)
    • Predoctoral stay, Prof. Luc Brunsveld (Chemical Biology, Eindhoven University of Technology)
    • Project associate researcher. Department of Organic and Inorganic Chemistry
    • Master Organic Synthesis Universidad Complutense de Madrid (2017/2018)
    • Graduated at the Universidad Complutense de Madrid (2013-2017)

    Publications in the group

    1,2,3-Benzotriazine Synthesis by Heterocyclization of p-Tosylmethyl Isocyanide Derivatives.
    J. Org. Chem. 2023, 88, 14131
    The pHLIP system as a vehicle for microRNAs in the kidney.
    Nefrologia. 2020, 40, 491

    Alvaro Gonzalez

    Alvaro Gonzalez Molina

    ublons: AAU-4665-2020

    • Project associate researcher (2024)
    • Thesis defense, 12.04.24. “Síntesis de aminoácidos bicíclicos y peptidomiméticos conformacionalmente restringidos derivados de prolina y ácido pipecólico”
    • Predoctoral stay, Prof. Maria Laura Bolognesi (BoMedChem Lab, Alma Mater Studiorum – Università di Bologna)
    • FPI grant MINECO 2019
    • Garantía Juvenil researcher (05.02.2018-04.02.2019)
    • Master Organic Chemistry Universidad Complutense de Madrid (2016-2017)
    • Graduated at the Universidad Complutense de Madrid (2012-2016)

    Isabel Valencia

    Isabel Valencia Nieto

    • Center for Applied Chemistry and Biotechnology – UAH, 02.2023-
    • Thesis defense, 21.07.2023
    • Predoctoral stay, Prof. Patrick G. Harran (University of California, Los Angeles, UCLA)
    • FPU grant Ministerio de Educación y Formación Profesional (2020-2023)
    • FPI grant Universidad de Alcalá (2019-2020)
    • REDINREN associate researcher Universidad Alcalá (2018)
    • Master Organic Chemistry Universidad Complutense de Madrid (2017-2018)
    • Graduated at the Universidad de Valladolid (2013-2017)

    Publications in the group

    Hyper-Cross-Linked Porous Polymer Featuring B-N Covalent Bonds (HCP-BNs): A Stable and Efficient Metal-Free Heterogeneous Photocatalyst.
    ACS Macro Lett. 2023, 12, 949
    β-Functionalization of 4 a-aza-8 a-boranaphthalene via Iridium-catalyzed C−H Borylation.
    Adv. Synth. Catal. 2023, 365, 2545
    Synthesis of Five-Membered Organoborate Heterocycles via a Metal-Free Carboboration and Their Use in Cross-Coupling Reactions.
    Synthesis 2023, 55, 1260
    1,10a-Dihydro-1-aza-10a-boraphenanthrene and 6a,7-Dihydro-7-aza-6a-boratetraphene: Two New Fluorescent BN-PAHs.
    J Org Chem. 2021 Nov 22. doi: 10.1021/acs.joc.1c01095.
    Expanding the BN-embedded PAH family: 4a-aza-12a-borachrysene.
    Chem Commun 2020, 56, 3669

    Jaime Tostado

    Jaime Tostado Sánchez

    • Master’s Degree in Secondary School Training (2024)
    • Postdoctoral Researcher Universidad de Alcalá (2024)
    • Thesis defense, 31.11.23
    • Predoctoral stay, Prof. M. Alcarazo (University of Göttingen)
    • FPI grant Universidad de Alcalá (2020-2024)
    • REDINREN associate researcher Universidad de Alcalá (2019)
    • Master Organic Chemistry, Universidad Complutense de Madrid (2017-2018)
    • Graduated at the Universidad de Salamanca (2013-2017)

    Publications in the group

    Synthesis of Seven- and Eight-Membered Rings by a Brønsted Acid Catalyzed Cationic Carbocyclization of Biphenyl Embedded Enynes.
    Org Lett. 2024 Apr 26;26(16):3343-3348. doi: 10.1021/acs.orglett.4c00647. Epub 2024 Apr 11.
    Plaza 3055
    Advanced Synthesis & Catalysis. 2024; 366(2):232 -240.

    Ester Sans

    Ester Sans Panadés

    • Thesis defense, 3.03.2023
    • FPI grant Universidad de Alcalá (2017-2021)
    • REDINREN associate researcher Universidad de Alcalá (2017)
    • Master Synthesis, Catalysis and Molecular Design, Universidad Rovira i Virgili (2017)
    • Graduated at the Universidad Rovira i Virgili (2016)

    Publications in the group

    Selective Synthesis of Boron-Functionalized Indenes and Benzofulvenes by BCl(3)-Promoted Cyclizations of ortho-Alkynylstyrenes.
    Org Lett. 2024, 26, 6568.
    Synthesis of BN-Polyarenes by a Mild Borylative Cyclization Cascade.
    Org Lett. 2022, 24, 5860

    Ana Milián

    Ana Milián López

    • Justesa Imagen S.A., 04.2021
    • Predoctoral stay, Prof. David Sarlah (Illinois University, Urbana-Champaign)
    • FPI grant Universidad de Alcalá (2016-2020)
    • REDINREN associate researcher Universidad de Alcalá (2016)
    • Master Food and nutrition, Universidad de Barcelona (2017)
    • Master Drug Discovery, Universidad Complutense de Madrid (2016)
    • Graduated at the Universidad de Barcelona (2014)

    Publications in the group

    Selective Synthesis of Boron-Functionalized Indenes and Benzofulvenes by BCl(3)-Promoted Cyclizations of ortho-Alkynylstyrenes.
    Org Lett. 2024, 26, 6568.
    Synthesis of Seven- and Eight-Membered Rings by a Brønsted Acid Catalyzed Cationic Carbocyclization of Biphenyl Embedded Enynes.
    Org Lett. 2024 Apr 26;26(16):3343-3348. doi: 10.1021/acs.orglett.4c00647. Epub 2024 Apr 11.
    Plaza 3055
    Advanced Synthesis & Catalysis. 2024; 366(2):232 -240.
    Synthesis of Phenanthrene-Based Polycycles by Gold(I)-Catalyzed Cyclization of Biphenyl-Embedded Trienynes.
    Adv. Synth. Catal. 2022, 364, 3960
    Metal-Free Temperature-Controlled Regiodivergent Borylative Cyclizations of Enynes: BCl(3) -Promoted Skeletal Rearrangement.
    Angew Chem Int Ed Engl. 2022, e202205651
    Selective Synthesis of Phenanthrenes and Dihydrophenanthrenes via Gold-Catalyzed Cycloisomerization of Biphenyl Embedded Trienynes.
    Org Lett. 2020, 22, 8464