22nd Tetrahedron Symposium

Lisbon, 28 June – 1 July

– Póster:
· Photocatalytic synthesis of indazoles from alkynylazobenzenes
Clara Mañas, Estíbaliz Merino

– Póster:
· Metal-free synthesis of medium-sized rings by cationic carbocyclization of trienynes
Jaime Tostado Sánchez, Ana Milián, Juan J. Vaquero, Manuel A. Fernández-Rodríguez

XXXVIII Reunión Bienal de la Real Sociedad Española de Química (RSEQ)

Granada, 27-30 June

– Oral:
· Asymmetric Photocatalysis Through Smiles Rearrangements
Estíbaliz Merino

– Oral:
· Drogas, fármacos y venenos: el impacto de los productos naturales en la historia
David Sucunza

– Póster:
· Progress towards the synthesis of Laetevirenol A
Lucía Sánchez Jiménez, Ana Milián, Jaime Tostado, Juan J. Vaquero, Patricia García García, Manuel A. Fernández Rodríguez

– Póster:
· Gold(I) catalyzed cyclization of alkynylcyclobutanamides towards lactams
Guillermo G. Otárola, María Soledad Garre, Estíbaliz Merino, David Sucunza, Juan J. Vaquero, Patricia García-García

– Póster:
· Catalytic (enantioselective) access to 4-(sec-alkyl)anilines via 1,6-conjugate addition of Grignard reagents to in situ generated aza-p-quinone methides
Mercedes Zurro, L. Ge, S. R. Harutyunyan

XXVIII REUNIÓN BIENAL del Grupo Especializado de Química Orgánica

Granada, 1 July

– Póster:
· Photocatalytic synthesis of a-chloro- and a-hydroxy b-sulfonylamides. Preparation of anticancer drug Bicalutamide
Sergio Torres, Mercedes Zurro, Estíbaliz Merino

– Póster:
· Preparation of 5-aryl-3-trifluoromethylpyrazoles: one-pot metal-free transformation from styrenes and 2,2,2-trifluorodiazoethane
Julia Altarejos, David Sucunza, Juan José Vaquero, Estíbaliz Merino, Javier Carreras

Introducing… Patricia in Angew Chem

Patricia García-García has published her first article as a submitting corresponding author in Angewandte Chemie:

Metal-Free Temperature-Controlled Regiodivergent Borylative Cyclizations of Enynes: BCl3-Promoted Skeletal Rearrangement: A. Milián, M. A. Fernández-Rodríguez, E. Merino, J. J. Vaquero, P. García-García, Angew. Chem. Int. Ed. 2022, doi.org/10.1002/anie.202205651.

https://onlinelibrary.wiley.com/doi/10.1002/anie.202207530

Metal-Free Temperature-Controlled Regiodivergent Borylative Cyclizations of Enynes: BCl3-Promoted Skeletal Rearrangement

Ana Milián, Manuel A. Fernández-Rodríguez,* Estíbaliz Merino, Juan J. Vaquero, Patricia García-García*

Angew. Chem. Int. Ed. 2022, Accepted Articles
DOI: 10.1002/anie.202205651

Dr. Modesto J. Remuiñán Blanco

Dr. Modesto J. Remuiñán Blanco, Project Leader, GlaxoSmithKline (GSK)
Enseñando nuevos trucos a un “perro viejo”: Reprogramando Etionamida para luchar contra la Tuberculosis Resistente
Sala de Grados, Edificio de Farmacia, UAH. May 6th, 12.00.

Modesto J. Remuiñán lecture

Prof. Olga García Mancheño

Prof. Olga García Mancheño, Organisch-Chemisches Institut/Universität Münster, Germany
Innovative Organocatalysts’ Design for Photoredox & Anion-Binding Catalysis
Aula de Grados, Edificio de Farmacia, UAH. April 19th, 12.00.

CKD: The burden of disease invisible to research funders

Alberto Ortiz et al.
Clin Kidney J. 2022, 15, 372
DOI: 10.1093/ckj/sfab170

RICORS2040: the need for collaborative research in chronic kidney disease

Alberto Ortiz et al.
Nefrología 2022, 42, 65
DOI: 10.1016/j.nefro.2021.09.004

Electrochemically Driven One-pot Oxidative Conversion of Arylhydrazines into Aromatic Iodides

Noemi Salardón, Guillermo Otárola, Clara Mañas, Estíbaliz Merino, Belen Batanero*

J. Environ. Chem. Eng. 2022, in press, Open access
DOI: 10.1016/j.jece.2022.107486

Prof. Francisco Corzana talk

Prof. Francisco Corzana, Universidad de La Rioja
Exploiting the use of unnatural glycopeptide based antigens to detect and fight cancer
Sala de Grados, Edificio de Farmacia, UAH. December 15th, 12.00.

(pictures 1, 2)

Prof. Álvaro Somoza talk

Prof. Álvaro Somoza, IMDEA Nanociencia Institute
Smart Nanomedicines Against Cancer
Sala de Grados, Edificio de Farmacia, UAH. December 3d, 12.00.

(pictures 1, 2)

XVII SIJ-RSEQ organisation

Several members of the group have been in charge of organising the 17th RSEQ Young Researchers Symposium, held in Alcalá de Henares from 23 to 26 November.

XVII Simposio de Investigadores Jóvenes de la RSEQ

The group has also made several contributions:

– Oral:
· Synthesis of seven- and eight-membered rings by Brønsted acid-catalyzed cyclization of biphenyl embedded trienynes
Jaime Tostado Sánchez, Juan J. Vaquero, Manuel A. Fernández-Rodríguez

– Flash:
· Enantio- and diastereoselective cyclopropanation of trans-alkenylboronates: Synthesis of versatile (trifluoromethyl)cyclopropylboronates
Julia Altarejos, David Sucunza, Juan José Vaquero, Javier Carreras

– Poster:
· Synthesis of a series of novel bicyclic amino acids
Álvaro González, Francisco José Torrero, José Luis Aceña, Juan José Vaquero

· Metal-free straightforward synthesis of boron-functionalized indenes and fulvenes by borylative cyclization
Ester Sans Panadés, Patricia García-García, Juan J. Vaquero, Cintia Virumbrales, Roberto Sanz, Manuel A. Fernández-Rodríguez

· SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) FOR THE TREATMENT OF CHRONIC KIDNEY DISEASE
Francisco Maqueda Zelaya, Verónica Miguel, José Luis Aceña, Santiago Lamas, Juan José Vaquero

· Synthesis of 4-membered rings fused lactams by gold(I) catalyzed
cyclization of alkynylcyclobutanamides
Guillermo G. Otárola, María Soledad Garre, Estíbaliz Merino, David Sucunza, Juan J. Vaquero, Patricia García-García

· Regioselective Ir-Catalyzed C−H Borylation of 4a,8a-Dihydro-4a-Aza-8a-Boranaphthalene
Isabel Valencia, Patricia García, David Sucunza, Juan J. Vaquero

· DEVELOPMENT OF A SYNTHETIC ROUTE TO LAETEVIRENOL A
Lucía Sánchez-Jiménez, Ana Milián, Jaime Tostado, Juan J. Vaquero, Patricia García-García, Manuel A. Fernández-Rodríguez

· Kinetic resolution in transannular Morita-Baylis-Hillman reaction:
approach to the synthesis of guaiane-type sesquiterpenes
Rubén Manzano, Raquel Mato, Efraím Reyes, Liher Prieto, Uxue Uria, Luisa Carrillo, Jose L. Vicario

· Electrochemical synthesis of aryl iodides from arylhydrazines
Clara Mañas Hernández, Guillermo Otárola, Estíbaliz Merino, Noemi Salardón, Belén Batanero