2011, Publicación

Maôas et al. Chemical Communications. 2011;47(26):7374 -7376. A V-shaped cationic dye for nonlinear optical bioimaging.

Publications > Maôas et al

Chem. Commun. 2011, 47, 7374

A V-shaped cationic dye for nonlinear optical bioimaging.

E. Maôas1, 2, G. Marcelo, S. Pinto, T. Cañeque, A.M. Cuadro, J.J. Vaquero, J.M.G. Martinho

1. Centro de Química-Física Molecular (CQFM), Institute of Nanoscience and Nanotechnology (IN), Instituto Superior Técnico, 1049-001 Lisboa, Portugal.  2. Departamento de Química Orgánica, Universidad de Alcalá, 28871-Alcalá de Henares, Madrid, Spain.

Resumen

A symmetric cationic molecule with D-π-A+-π-D architecture was synthesized with high two-photon absorption cross-section (σ2 ≈ 1140 GM). Application as a marker in fluorescence microscopy of living cells revealed its presence inside the cell staining vesicular shape organelles in the cytoplasm. Fluorescence lifetime imaging microscopy shows that it is also able to penetrate within the nucleus. © 2011 The Royal Society of Chemistry.

graphical abstract