Deligeorgiev et al. Coloration Technology. 2010;126(1):24 -30. Novel environmentally benign procedure for the synthesis of 2-aryl- and 2-hetaryl-4(3H)-quinazolinones

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Novel environmentally benign procedure for the synthesis of 2-aryl- and 2-hetaryl-4(3H)-quinazolinones

Resumen

A novel environmentally benign procedure for the synthesis of 2-aryl- or 2-hetaryl-4(3H)-quinazolinones by condensation of anthranilamide with various aromatic aldehydes in polyethylene glycol under microwave irradiation has been developed. In contrast with other reported methods, this procedure provides the corresponding quinazolinones with good to high yields and purity, in very short reaction times and without the use of an oxidant.