Deligeorgiev et al. Ultrasonics Sonochemistry 2010;17(5):783 -788. An easy and fast ultrasonic selective S-alkylation of hetaryl thiols at room temperature

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An easy and fast ultrasonic selective S-alkylation of hetaryl thiols at room temperature

Resumen

A series of 2-alkylthio derivatives of hetaryl thiols were synthesized by selective S-alkylation with alkyl halides (bromides and iodides) with ultrasonic irradiation at room temperature. The reaction was found to be generally applicable to hetaryl thiol derivatives with different substituents in the aromatic nucleus and various alkyl halides. The reaction gives high to excellent yields of products with high purity.