Full Professor, Organic Chemistry, (Universida Complutense de Madrid),
Head of the MedChemLab
Nuevas estrategias terapéuticas para el tratamiento de la progeria
Friday, October 10 · 12:30 h, Sala de grados, Faculty of Pharmacy
Online: https://eu.bbcollab.com/guest/0268bb035b344144b6dcfcb06ec3b92e
Full Professor, Inorganic Chemistry, (Universidat de Barcelona),
Head of the Supra and Nanostructured Systems Group
Harnessing Self-Assembly for Smart Materials: Sensors, tuning light, and Catalytic Functions
Thursday, October 2 · 12:30 h, Sala de grados, Faculty of Pharmacy
Online: https://eu.bbcollab.com/guest/0268bb035b344144b6dcfcb06ec3b92e
The QuiBio Group is welcoming two new members, Marina and Lorena!
The Biological Chemistry Research Group is thrilled to have two new PhD students join the team as project research associates. Marina will be working with Dr. Javier García Marin on new protein-protein interaction disruptors to fight against fibrosis, while Lorena will be under the supervision of Dr. Ángela Martín-Serrano to discover bifunctional molecules as antibody-recruiting agents.
We wish them both the best of luck with their doctoral theses and are excited to see the contributions they’ll make to our research!
Our PhD candiate, Marta Durán, has participated in the the first edition of MEDCHEMXCHANGE, a new webinar series launched by the Sociedad Española de Química Terapéutica (SEQT) Early Career Scientists (SEQT-ECS) group.
Sergio Torres-Oya, Manuel A. Fernández-Rodríguez, Mercedes Zurro*
Compounds containing tricyclic bridgehead carbon centers are privileged structures in drug discovery. In this work, two different polycyclic scaffolds containing this substructure have been accessed by divergent gold-catalyzed cycloisomerizations of o-cyclopropylidenemethyl-o′-alkynylbiaryls. Selectivity towards one or the other scaffold is mainly controlled by temperature. The electronic nature of the arene group at the alkyne also plays a significant role, which is explained based on the proposed mechanism.
Adv. Synth. Cat. 2025
DOI: 10.1002/adsc.202500244
Our group member, Sergio Torres Oya, has participated in the Dream Reactions Symposium 2025 held in Münster (Germany) with a poster.
· Enantioselective copper (ii) catalysed (4+1) cycloaddition of Aza-o-quinone methides and bromomalonates: facile access to chiral Indolines
Sergio Torres-Oya, Manuel A. Fernández-Rodríguez, Mercedes Zurro
Lucía Sánchez, Adrián Gargantiel, Manuel A. Fernández-Rodríguez,* Patricia García-García*
Compounds containing tricyclic bridgehead carbon centers are privileged structures in drug discovery. In this work, two different polycyclic scaffolds containing this substructure have been accessed by divergent gold-catalyzed cycloisomerizations of o-cyclopropylidenemethyl-o′-alkynylbiaryls. Selectivity towards one or the other scaffold is mainly controlled by temperature. The electronic nature of the arene group at the alkyne also plays a significant role, which is explained based on the proposed mechanism.
Org. Chem. Front. 2025
DOI: 10.1002/adsc.202500244
Our PhD student, Lucía Sánchez, has participated in the 23rd European Symposium on Organic Chemistry congress in Copenhagen with a poster:
Synthesis of dibenzoheptafulvenes by gold-catalyzed cyclization of o-alkenyl-o`-alkynylbiphenyls in the presence of nucleophiles
Lucía Sánchez-Jiménez, Patricia García-García, Manuel Ángel Fernández-Rodríguez
orcid.org/
This inaugural session was organized in collaboration with the EFMC Young Scientists Network (YSN) as part of their #LunchandLearn initiative.