Copper-Catalyzed Hydroamination of 2-Alkynylazobenzenes: Synthesis of 3-Alkenyl-2H-Indazoles
Lucía Sánchez-Jiménez, Patricia García-García, Manuel Á. Fernández-Rodríguez*
Electrophilic cyclizations of biaryl-embedded 1,7-enynes enable the selective synthesis of dibenzofused polycycles with diverse topologies. The outcome strongly depends on the promoter—gold(I) complexes, Brønsted acids, or electrophilic boron reagents—as well as the substitution pattern of the enyne. This Account highlights recent advances and establishes a basis for future developments through the controlled design of substrates and activation modes.
Congratulations to our PhD student Belén Ibarra for winning the Best Poster Prize at the XXI Symposium of Young Researchers of the RSEQ in Zaragoza. Belén is doing her thesis under the supervision of Dr. Estibaliz Merino.
Divergent synthesis of two polycyclic frameworks containing tricyclic bridgehead carbon centers by gold-catalyzed cycloisomerization of o-cyclopropylidenemethyl-o′-alkynylbiaryls.
We are pleased to announce that Dr. Clara Mañas has been awarded the prize for the best doctoral thesis in the Health Sciences category by the Sociedad de Condueños.
Dr. Mañas award-winning thesis, titled “Design and study of novel reactivities of alkynylazobenzenes,” represents a significant contribution to the field. The award recognizes the exceptional quality and originality of her research.
The Society of Condueños Awards are given annually to recognize excellence in academic and cultural fields.The Society collaborates with key institutions in Alcalá to grant these prestigious awards, which celebrate the best doctoral theses across several disciplines at the Universidad de Alcalá
The QuiBio Group is welcoming two new members, Marina and Lorena!
The Biological Chemistry Research Group is thrilled to have two new PhD students join the team as project research associates. Marina will be working with Dr. Javier García Marin on new protein-protein interaction disruptors to fight against fibrosis, while Lorena will be under the supervision of Dr. Ángela Martín-Serrano to discover bifunctional molecules as antibody-recruiting agents.
We wish them both the best of luck with their doctoral theses and are excited to see the contributions they’ll make to our research!
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This inaugural session was organized in collaboration with the EFMC Young Scientists Network (YSN) as part of their #LunchandLearn initiative.