All posts by Javier García Marín

2025, Noticias, Uncategorized

XL Reunión Bienal de la RSEQ

Our group was well-represented at the XL Meeting of Chemistry of the RSEQ in Bilbao! We’re proud to announce that our team presented posters, flash communications, and two oral communications, sharing our latest research.

 

– Flash:
· Acid-mediated cationic cyclization of o-acryloyl-o’-alkynylbiaryls for the synthesis of fluorescent functionalized polycycles
Alex Hipólito-Barriuso, Jaime Mateos, Patricia García-García, Manuel A. Fernández-Rodríguez

 

– Poster:
· Light-induced C–C bond cleavage/C–N formation in homobenzylic
sulfonamides with N-iodoimides
Guillermo Morales-Ortega, Estíbaliz Merino, Javier Carreras

– Poster:
· Exploring the potential of scaffolding activation of ilk using small molecules
Marta Durán Martínez, Mercedes Griera Merino, José Luis Aceña,1 Laura Calleros, Sergio de Frutos García, Diego Rodríguez Puyol, Javier García Marín

–  Poster:
· Synthesis of 2,4,6-trisubstituted pyridines by Heterocyclization of TosMIC Derivatives
Jose Antonio García-García, Jose Luis Aceña Bonilla, David Sucunza.

– Poster:
· Enantioselective copper (ii) catalysed (4+1) cycloaddition of Aza-o-quinone methides and bromomalonates: facile access to chiral Indolines
Sergio Torres-Oya, Manuel A. Fernández-Rodríguez, Mercedes Zurro

Noticias

Dr. Julia Altarejos and Dr. Clara Mañanas Extraordinary Doctorate Awards

Dr. Julia Altarejos and Dr. Clara Mañas, researchers from the Chemical Biology Group, have been awarded the prestigious Extraordinary Doctorate Award by the University of Alcalá for the 2023-2024 academic year.

This annual honor recognizes the most exceptional doctoral theses presented at the university. Dr. Altarejos completed her doctoral studies under the supervision of Dr. Javier Carreras, while Dr. Mañanas was supervised by Dr. Estibaliz Merino.

The Chemical Biology Group congratulates both researchers on this significant achievement, which recognizes the outstanding quality and impact of their work.

Congrats Clara and Julia!!

Noticias

Johnson & Johnson SEQT Prize – Marta Durán

Marta Durán Martínez won Johnson & Johnson Prize of Sociedad Española de Química Terapéutica (SEQT) para Investigadores Noveles en el Campo de la Búsqueda y desarrollo de Nuevos Fármacos. Congratulations!

The award was received during the 19th Meeting of the Spanish Society of Medicinal Chemistry, Vitoria.
Flash communication:
Unveiling the therapeutic potential of the integrin-linked kinase with small molecules

2025, Noticias

Chem. Sci. 2025

Visible-light-initiated metal-free Csp3–Csp3 to Csp3–N conversion in homobenzylic sulfonamides with N-iodoimides

Guillermo Morales-Ortega,   Estíbaliz Merino  and  Javier Carreras*

We report a simple protocol for the transformation of Csp3–Csp3 to Csp3–N in homobenzylic sulfonamides in combination with N-iodoimides to form gem-diamino derivatives. The reaction exhibits a wide functional group tolerance and allows the incorporation of bioactive-derived fragments. The mechanistic insights provided by control experiments and DFT calculations suggest that an imine intermediate is formed after C−C bond cleavage.

Chem. Sci. 2025
DOI: 10.1039/D5SC02168E

Miembros

Ángela Martín-Serrano

 

Ángela Martín-Serrano Ortiz

  • 2025: Senior Research Fellow, Talent Attraction Program of Community of Madrid.
  • 2021: Postdoctoral Researcher. Université Grenoble-Alpes (Grenoble, France).
  • 2018: Postdoctoral Researcher at Universidad de Alcalá (Madrid, Spain).
  • 2018: PhD at the Biomedical Research of Malaga-IBIMA (Málaga, Spain)
  • 2017: FEBS Summer Fellowship. Royal Institute of Technology-KTH (Stockholm,Sweden)
  • 2013: Research Assistant at Universitary School of Mining and Industrial Engineering of Almadén-EIMIA, (Spain)
  • 2012: Research Assistant at NanoMyP S.L. (Santander-CRUE-CEPYME grant), Granada (Spain)
  • 2012: Master’s Degree in Biological Analysis and Laboratory Diagnostics, Universidad de Granada (Spain)
  • 2011: Graduated in Chemistry at Universidad de Castilla-La Mancha (Spain)